The Pattern of Bacterial Colonization and Urinary Tract Infection following endo- urological operations with double J Stent. A descriptive study.

Abstract

Introduction: Double J (DJ) ureteral stents are commonly utilized to alleviate urinary blockages but are susceptible to bacterial colonization and the formation of biofilms, which heightens the likelihood of multidrug-resistant infections, including those caused by ESKAPE pathogens. It is essential to comprehend colonization trends and antibiotic susceptibility to inform preventive and treatment approaches.

Methods: A descriptive observational study was carried out involving 110 patients receiving DJ stenting, examining demographics, stent retention periods, bacterial colonization in urine and stent cultures, and antibiotic resistance profiles via standard microbiological methods.

Results: Bacterial colonization was identified in 19.1% of urine specimens and 29.1% of cultures from DJ stents. Escherichia coli was the predominant isolate, with significant occurrences of Klebsiella, Pseudomonas, and Acinetobacter species. The average duration of stent placement was 21.4 days, with the majority of patients (76.4%) retaining stents for more than 14 days. Sensitivity testing indicated favorable responses to amikacin, Piperacillin/Tazobactam, levofloxacin, and nitrofurantoin, while certain resistant strains required colistin or tigecycline.

Conclusion: Extended DJ stenting elevates the risk of colonization by ESKAPE organisms, underscoring the importance of infection control measures, antibiotic stewardship, and the potential use of antimicrobial-coated stents to mitigate multidrug-resistant infections.